Non-Surgical Embryo Transfer Device

NSET Device




NSET – Non-Surgical Embryo Transfer Device

The NSET device revolutionises embryo transfer in pseudopregnant mice, making it ideal for producing transgenic or knock-out mice without surgery. The NSET device attaches to a P-2 pipette to allow for the transcervical transfer of embryos. NSET technology is as effective as current embryo surgical procedures, but requires significantly less time to master than traditional surgery.

NSET Device Uses:

  • Embryo transfer after DNA microinjection
  • Transfer of ES cell chimeric blastocysts
  • Transfer of cryopreserved embryos
  • Transfer of cells after in vitro fertilisation
  • Embryo transfer for rederivation

Advantages of using the NSET:

  • Reduces costs of embryo transfer up to 75%
  • Eliminates the pain and distress of surgery
  • No anaesthesia required
  • Eliminates need for post-surgical monitoring of animals
  • Reduces regulatory burden by eliminating need to justify survival surgery
  • Eliminates surgical instruments and time consuming pre andpost surgical processes
  • Greatly reduces time required to become proficient in embryo transfer


NSET Device Cost Analysis

 Surgical ProceduresNSET Procedures
Minutes Per Procedure*602
Labour & Overhead/Minute**60 x £1.042x £1.04
Labour & Overhead Cost/Procedure£62.40£2.08
Consumable Cost of NSET***N/A36.00
Total Cost of Procedure£62.40£38.08
NSET Price Reduction39%
* Includes pre and postoperative care. **Overhead cost per facility will vary.
*** Cost analysis does not include reduction of surgical consumables.


Non-Surgical Embryo Transfer Device (NSET Device) from reveal on Vimeo
The Non-Surgical Embryo Transfer (NSET) device, which was developed at the University of Kentucky, represents a significant advance in the transfer of mouse embryos


Datesand is the exclusive European distributor
of theNSET Device developed by ParaTechs!

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